口服营养补充剂与或没有多域干预计划对老年人认知功能和整体健康的影响:一项随机对照试验
Hae-Jin Kang1, Eun-Hye Lee2, Seong-Hye Choi3
1Department of Medical Nutrition, AgeTech-Service Convergence Major, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Republic of Korea.
Nutrients
|June 13, 2025
概括
将口服营养补充剂 (ONS) 与多领域干预计划 (MIP) 结合起来,显著改善了轻度认知障碍患者的认知功能. 这种综合方法也提高了饮食行为和身体表现,与单独的ONS不同.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 营养科学 营养科学
背景情况:
- 痴呆症的患病率在全球范围内不断上升,增加了社会经济负担.
- 对轻度认知障碍 (MCI) 的早期干预对于预防和治疗至关重要.
- 口服营养补充剂 (ONS) 和多领域干预 (MIP) 是认知健康的潜在策略.
研究的目的:
- 评估一个为期8周的口服营养补充剂 (ONS) 计划,有或没有多领域干预计划 (MIP),对轻度认知障碍 (MCI) 患者的影响.
主要方法:
- 49名MCI患者被分配到三个组:ONS,ONS+MIP和对照组 (CON).
- 在ONS+MIP小组获得了韩国风格的痴呆症预防MIP与ONS.
- 认知功能 (RBANS),营养状况,身体组成和身体表现在8周干预之前和之后进行了评估.
主要成果:
- 与基线相比,ONS+MIP组在认知功能 (RBANS分数) 中显著改善.
- 在ONS或CON组中没有观察到显著的认知变化.
- ONS+MIP组在饮食行为,食物质量,握力,肌肉耐力和总SPPB得分方面表现出改善,而CON组的SPPB得分下降.
结论:
- 多领域干预,结合口服营养补充剂和密集教育,对于提高MCI患者的认知功能至关重要.
- 持续监测和综合计划比单独补充剂对认知健康更有效.
- 这项研究强调了营养支持和有针对性的干预措施对管理轻度认知障碍的协同效应.
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