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癌手术中伤口并发症的危险因素和重建手术的指示
Justin J E Delahaije1,2, Ephrahim E Jerry1, Saskia Houterman3
1Department of Gynecology, Catharina Hospital Eindhoven, 5623 EJ Eindhoven, The Netherlands.
重建性手术 (RS) 增加了癌手术后的伤口并发症,以及较大的瘤和特定位置. 在癌患者可行的情况下,可以优先选择初级关闭 (PC).
科学领域:
- 妇科瘤学 妇科瘤学
- 手术瘤学手术瘤学
- 伤口治愈研究研究 伤口治愈研究
背景情况:
- 癌手术经常导致严重的术后伤口并发症.
- 重建性手术 (RS) 通常用于广泛的部瘤或复发.
研究的目的:
- 为了确定癌手术后伤口并发症的发生率和风险因素.
- 为了比较初级关闭 (PC) 与重建性手术 (RS) 对伤口并发症率的影响.
主要方法:
- 在四个荷兰妇科瘤中心 (2018-2022) 进行了回顾性队列研究.
- 在接受PC和RS的患者中分析伤口并发症.
- 后勤回归用于识别风险因素,调整混变量.
主要成果:
- 总共有394名妇女被纳入 (318名PC,76名RS).
- 伤口并发症的总发病率为46.7%,伤口破裂是最常见的并发症 (42.4%).
- 在多变量分析后,重建性手术 (RS) 与增加伤口并发症风险 (OR 1.2;95% CI 1.1-1.2) 显著相关,尽管还确定了瘤大小和位置等其他因素.
结论:
- 癌手术伤口并发症的关键风险因素包括较大的瘤大小,接近尿道,尿道切除和围位置.
- 重建性手术 (RS) 是增加伤口并发症的独立风险因素,可能是由于患者和瘤选择标准.
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