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不确定性不耐受对乳腺癌患者在化疗前认知的认知功能的影响
Yesol Yang1,2, Alai Tan1, Sagar D Sardesai3
1College of Nursing, The Ohio State University, Columbus, OH 43210, USA.
Cancers
|June 13, 2025
概括
不确定性不耐受性 (IU) 与乳腺癌患者在化疗前的认知障碍有关. 焦虑作为一个关键的调解者,表明IU的早期评估可以帮助识别有风险的患者.
科学领域:
- 在瘤学瘤学.
- 心理学 心理学 心理学
- 神经科学是一个神经科学.
背景情况:
- 与癌症相关的认知障碍 (CRCI) 是乳腺癌患者的常见问题.
- 导致化学疗法未经治疗的患者CRCI的因素需要用于早期干预的识别.
- 了解化疗前的因素对于预防CRCI恶化至关重要.
研究的目的:
- 研究乳腺癌患者在化疗前不容忍不确定性 (IU) 和认知功能之间的关系.
- 为了确定焦虑是否调解了IU和认知功能之间的关联.
主要方法:
- 该研究包括58名被诊断为I-III期乳腺癌的女性患者,预计将接受化疗.
- 收集的数据包括认知功能,IU,焦虑水平和其他相关患者信息.
- 进行了统计分析,以检查关联和调解效应.
主要成果:
- 较高的IU显著与增加的焦虑水平有关.
- 随后,增加的焦虑与这些患者的认知功能低下有关.
- 焦虑在很大程度上调解了IU与认知功能之间的关系 (间接效应β = -0.19,总效应β = -0.2).
结论:
- 对不确定性的不容忍显著影响乳腺癌患者的认知功能.
- 建议在化疗前评估IU,以早期发现认知障碍风险.
- 向IU可能为管理CRCI提供预防策略.
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