维生素C作为术后疼痛管理中的辅助止痛疗法
Wioletta Mędrzycka-Dąbrowska1, Sandra Lange2, Sebastian Dąbrowski3
1Department of Anaesthesiology Nursing & Intensive Care, Faculty of Health Sciences, Medical University of Gdansk, Dębinki 7, 80-211 Gdańsk, Poland.
Journal of clinical medicine
|June 13, 2025
概括
在外科手术期间给予维生素C显著降低了术后疼痛强度,并减少了对阿片类止痛药的需求. 这表明维生素C (酸) 可能是多式联络疼痛管理策略的宝贵补充.
科学领域:
- 麻醉学 麻醉学
- 疼痛管理 疼痛管理
- 营养科学 营养科学
背景情况:
- 手术后的疼痛影响了大约80%的手术患者.
- 阿片类药物是治疗疼痛的标准药物,但有副作用.
- 多模式止痛策略旨在减少阿片类药物依赖.
研究的目的:
- 审查维生素C对术后疼痛强度的影响.
- 评估维生素C对手术后阿片类药物消费的影响.
主要方法:
- 在2024年第四季度进行的系统审查.
- 搜索了PubMed,CINAHL,科学网络和科克兰图书馆.
- 包括14项评估疼痛强度和阿片类药物使用的研究.
主要成果:
- 所有包括的研究都显示,与安慰剂相比,使用维生素C可以减少疼痛强度.
- 在外科手术期间服用维生素C降低了阿片类药物消耗.
- 剂量范围为1-3g或50mg/kg静脉注射.
结论:
- 周围的维生素C可以减少疼痛强度和阿片类药物需求.
- 维生素C可以整合到外科手术患者的多模式止痛药中.
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