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Updated: May 6, 2026

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bTRM 控制小鼠细胞巨乳病毒中枢神经系统的重新激活

Priyanka Chauhan1, Shuxian Hu1, Wen S Sheng1

  • 1Neurovirology Laboratory, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

International journal of molecular sciences
|June 13, 2025
PubMed
概括

大脑组织内存T细胞 (bTRMs) 控制在中枢神经系统 (CNS) 中小鼠细胞巨血病毒 (MCMV) 的重新激活. 削减bTRMs可以使病毒重新激活,并改变微质表型.

关键词:
鼠类细胞巨型病毒 (MCMV)组织居民记忆T细胞 (bTRMs)病毒的重新激活.

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Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
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