亲溶解巨诱导的IL-35+但不是TGF-β1+ 调节性B细胞激活 需要PD-L1/PD-1通路

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Updated: Jun 16, 2025

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Guoqin Cao1,2, Takumi Memida1, Shengyuan Huang2

  • 1Department of Oral Science and Translational Research, College of Dental Medicine, Nova Southeastern University, 3200 South University Drive, Fort Lauderdale, FL 33328, USA.

International journal of molecular sciences
|June 13, 2025
PubMed
概括

亲溶解的M2巨细胞通过PD-L1/PD-1信号传导诱导调节性B细胞 (Breg),促进IL-35的表达. 这种相互作用对免疫平衡至关重要,突出了炎症解决的新型调节机制.

关键词:
在PD-L1中.这就是TGF-β.介质蛋白 35 介质蛋白 35巨细胞是一个巨细胞.监管B单元中的监管B单元.

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