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Updated: Jun 16, 2025

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药理 HIF-PH 抑制通过持续的 HIF-1α 稳定抑制肌细胞分化

Yuya Miki1, Akinobu Ochi1, Hideki Uedono1

  • 1Department of Metabolism, Endocrinology and Molecular Medicine, Osaka Metropolitan University Graduate School of Medicine, Osaka 545-8585, Japan.

International journal of molecular sciences
|June 13, 2025
PubMed
概括

缺氧诱导因子酸酶 (HIF-PH) 抑制剂稳定缺氧诱导因子-1α (HIF-1α),但可以抑制骨肌肉的分化. 这项研究表明,持续的HIF-1α稳定在体外和体内抑制肌细胞分化.

关键词:
在HIF-1α稳定过程中.这是一种HIF-PH抑制剂.肌肉分化 肌肉分化

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