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探索唾液硫酸盐作为身体活动反应的新生物标志物

Christoforos Chrimatopoulos¹, Kalliopi Papadopoulou¹, Theodora Tsilouli¹

¹Department of Chemistry, School of Sciences, University of Ioannina, 45110 Ioannina, Greece.

Molecules (Basel, Switzerland)

|June 13, 2025

概括

Salivary thiocyanate (SCN-) 水平在运动期间下降,表明其作为监测运动员生理压力的新生物标志物的潜力. 这项研究探讨了它在受控和现实世界的环境中对身体活动的反应.

科学领域:

运动生理学运动生理学
生物标志物发现发现
唾液诊断唾液诊断唾液诊断

背景情况:

Salivary thiocyanate (SCN-) 以其粘膜防御和抗氧化特性而闻名.
它对体力活动的反应和作为运动生物标志物的潜力仍未得到研究.
了解运动期间的唾液SCN动态可以提供对生理压力的见解.

研究的目的:

调查唾液硫酸盐 (SCN-) 作为一种对运动有反应的新生物标志物.
量化评估身体炼期间的唾液中SCN变化.
验证SCN-作为运动群体的非侵入性标记物.

主要方法:

验证了一种标准的Vis-光度法,用于快速定量唾液硫酸盐.
实施一个受控的跑步机协议,增加运动强度 (20%,60%,90% VO2max).
在训练之前和训练后,对各种体育运动的162名运动员进行了实地采样.

主要成果:

在受控和现场设置中,唾液酸盐度在应对身体炼时始终下降.
在增量运动和典型训练期间观察到SCN-水平的统计显著下降.
亚组分析显示了基于性别和吸烟状况的个体间差异.

结论:

这是第一个在体力炼期间定量确定唾液硫酸盐 (SCN-) 水平的研究.
唾液SCN-显示出作为监测运动员生理压力和免疫反应的非侵入性生物标志物的潜力.
这些发现为运动群体的唾液诊断开辟了新的途径.

关键词:

多元化的运动员队列.运动诱导的生物标志物非侵入性的唾液采样.用光度分析进行分析.身体炼就是体力炼.运动生理学体育生理学

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