在ICU老年患者中通过5因素修改的虚弱指数提高 Delirium 预测
Xinya Li1, Hongtao Cheng2, Yonglan Tang1
1School of Nursing, Jinan University, Guangzhou, China.
Nursing in critical care
|June 13, 2025
概括
虚弱,通过5因素修改的虚弱指数 (mFI-5) 测量,显著增加了老年重症监护室 (ICU) 患者的妄想风险. mFI-5有助于识别高风险个体,以便及时进行干预.
科学领域:
- 老年医学 老年医学
- 关键护理医学 关键护理医学
- 临床流行病学临床流行病学
背景情况:
- 狂妄和虚弱在ICU中很常见,特别是在老年人中.
- 有限的研究已经探索了5因素修改的脆弱指数 (mFI-5) 和这种人群中的妄想之间的联系.
研究的目的:
- 调查老年ICU患者mFI-5和痴呆发生之间的关联.
- 评估mFI-5在这个人口群体中对妄的预测能力.
主要方法:
- 使用了来自密集护理IV (MIMIC-IV) 数据库的医疗信息中心的数据.
- 将患者分为非脆弱 (mFI-5=0),中等脆弱 (mFI-5=1) 和高度脆弱 (mFI-5≥2) 的组.
- 使用曲线下的面积,净重新分类改进和综合歧视改进来评估预测值.
主要成果:
- 在30,280名ICU患者中, Delirium影响了9,919人.
- 与非脆弱患者相比,中等脆弱性 (aOR: 1.38) 和高脆弱性 (aOR: 1.83) 与明显更高的妄想风险有关.
- 将mFI-5集成到多变量模型中,提高了妄想预测的准确性.
结论:
- 根据mFI-5的判断,虚弱与老年ICU患者 Delirium 风险增加密切相关.
- mFI-5可以提高妄想模型的预测准确性.
- mFI-5是识别有风险的老年ICU患者的一个有价值的工具,促进早期干预.
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