扩展光谱β-乳糖酶在马来西亚中半岛的物猫和狗中产生大肠杆菌
Khaleeda Azalea Dzulkifli1, Latiffah Hassan2, Zunita Zakaria1,3
1Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, Malaysia.
Veterinary medicine and science
|June 13, 2025
概括
物中的抗菌素耐药性是一个越来越令人担忧的问题. 这项研究在马来西亚10.6%的健康猫和狗中发现产生扩展谱β-乳糖酶 (ESBL) 的大肠杆菌,而狗具有更高的风险.
科学领域:
- 兽医微生物学 兽医微生物学
- 抗微生物耐药性 抗微生物耐药性
- 动物传播疾病 动物传播疾病
背景情况:
- 有限的数据存在于马来西亚的物作为抗菌素耐药细菌的水库.
- 了解与物相关的抗菌素耐药性对于公共卫生至关重要.
研究的目的:
- 确定马来西亚半岛物猫和狗中产生扩展谱β-乳糖酶 (ESBL) 的大肠杆菌的流行情况.
- 确定与物中产生ESBL的大肠杆菌携带相关的风险因素.
主要方法:
- 一项涉及160只身体健康的物猫和狗在克朗谷 (2019-2020) 的横截面研究.
- 收集了直肠拭子以隔离大肠杆菌和检测ESBL.
- 使用问卷和统计分析来确定风险因素.
主要成果:
- 在10.6%的物 (6.8%的狗,3.8%的猫) 中检测到产生ESBL的大肠杆菌.
- 观察到高水平的多药耐药性,其中100%的耐药性是对安皮西林,塞法莱克辛和塞福塔克西姆的.
- 狗的携带ESBL产生大肠杆菌的可能性是猫的四倍. 分享养区域和胃肠道症状史是狗的危险因素.
结论:
- 马来西亚的物猫和狗携带ESBL产生的大肠杆菌,表明它们作为抗菌素耐药性 (AMR) 的储存库.
- 对多种抗生素的高共同耐药性需要谨慎的抗菌管理.
- 物和人类之间AMR基因的传播潜力强调了One Health方法的重要性.
关键词:
埃舍里希亚大肠杆菌 (Escherichia coli) 是一个大肠杆菌.抗微生物药物耐药性 抗微生物药物耐药性在β-lactamases中.猫 猫 猫 在线观看狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗更多相关视频
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