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Updated: Jun 15, 2025

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塞菲德罗科尔是"被围困的"吗? 了解NDM介导的新型药物耐药性的增加

Brenda A Warecki1, Pablo E Tomatis1,2, María F Mojica3,4,5

  • 1Instituto de Biología Molecular y Celular de Rosario (IBR), CONICET, Universidad Nacional de Rosario Rosario Argentina vila@ibr-conicet.gov.ar.

Chemical science
|June 13, 2025
PubMed
概括

抗菌素耐药性 (AMR) 正在上升,金属β-乳糖酶 (MBLs) 构成重大威胁. 塞菲德罗科尔 (FDC) 对一些MBLs表现出耐药性,但NDM变种可以使其失活,需要谨慎和潜在的组合疗法.

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