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Updated: Jun 15, 2025

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一个TiME的问题:微环境相互作用如何塑造CLL和里希特转换中的免疫治疗反应

Alexander F Vom Stein1,2,3, Phuong-Hien Nguyen1,2,3, Elisa Ten Hacken4

  • 1Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Cologne, Germany.

Frontiers in immunology
|June 13, 2025
PubMed
概括

免疫疗法在里希特转换 (RT) 和慢性淋巴细胞白血病 (CLL) 中表现有前途,但面临挑战. RT和CLL之间的瘤免疫微环境 (TiME) 的差异影响治疗的有效性.

关键词:
里克特的转换 里克特转换慢性淋巴细胞白血病 慢性淋巴细胞白血病临床试验中的临床试验.免疫疗法 免疫疗法微观环境是一个微观环境.鼠标模型 鼠标模型临床前研究 临床前研究

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