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与三糖糖指数相关的不同肥胖指数和肉症之间的关联:一个横截面研究

Wentao Xiao¹, Taichuan Xu¹, Yitao Liao¹

¹Department of Graduate School, Nanjing University of Chinese Medicine, Nanjing, China.

Frontiers in endocrinology

|June 13, 2025

概括

与甘油三糖 (TyG) 相关的新型肥胖指数显示,与美国人口中肉类的患病率有很强的关联. 经TyG重量调整的腰部指数 (TyG-WWI) 证明了对预测肉症的最佳诊断疗效.

科学领域:

代谢健康和肥胖研究研究.
老年医学和萨科佩尼亚研究研究.
公共卫生和营养流行病学.

背景情况:

与甘油三糖 (TyG) 指数相关的肥胖指数和肉症之间的关系在美国人口中仍然未经检查.
标志着肌肉质量和力量的损失的萨尔科佩尼亚是越来越严重的公共卫生问题,特别是在老年人群中.
了解肉症风险的新型指标对于早期检测和干预策略至关重要.

研究的目的:

为了研究与TyG指数相关的新型肥胖指数与美国队列中皮症患病率之间的关联.
为了比较这些指数的诊断性能与传统的TyG指数来预测肉症.
确定可靠的肥胖指标,以评估和预测肉症.

主要方法:

国家健康和营养检查调查 (2011-2018) 数据的横截面分析,来自4804名参与者的数据.
权重多变量逻辑回归被用来分析TyG-WHtR,TyG-WWI,TyG-WC,TyG-BMI和肉症之间的相关性.
接收器运行特征 (ROC) 分析评估了萨科佩尼亚指数的诊断有效性.

主要成果:

TyG-WHtR,TyG-WWI,TyG-BMI和TyG-WC显示出与肉类的患病率有显著的积极关联.
与最低四分位数 (OR=81.89) 相比,TyG-WWI的顶部四分位数表现出与最低四分位数相比,肉症的几率明显更高.
与TyG指数相比,所有四个测试指数都表现出了与TyG指数相比,对肉类的诊断效果更好,TyG-WWI显示出最佳性能 (AUC=0.802).

结论:

TyG-WWI,TyG-WHtR,TyG-BMI和TyG-WC与增加的肉症患病率有显著联系.
这些与TyG相关的肥胖指数,特别是TyG-WWI,在预测肉症方面表现优于标准TyG指数.
TyG-WWI显示出作为一种可靠和可访问的指标,用于评估和预测肉类的风险.

关键词:

尼汉斯 (NHANES) 是一个名人.在TyG指数中,TyG是指数.与TyG相关的肥胖指数跨截面研究是跨截面研究.这种类型的麻症是sarcopenia.

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