在常见的儿科疾病中早期的肠道微生物组:作用和治疗影响
1Department of Nutrition and Food Science, University of Maryland, College Park, MD, United States.
Frontiers in nutrition
|June 13, 2025
概括
早期的肠道微生物群对儿科健康至关重要. 在前三年内肠道微生物的不平衡会导致儿童疾病并影响成年人的健康.
科学领域:
- 微生物学 微生物学
- 儿科 儿科 儿科
- 免疫学 免疫学 免疫学
背景情况:
- 肠道微生物组是在生命早期建立的,并受到环境因素的影响.
- 早期的微生物失调与各种儿科疾病有关,包括IBD,过敏,ADHD和肥胖.
- 发育中的肠道微生物组在塑造宿主免疫和代谢反应方面发挥着至关重要的作用.
研究的目的:
- 审查当前对早期肠道微生物组在儿科疾病中的作用的理解.
- 讨论针对早期肠道微生物组的潜在干预措施.
主要方法:
- 这是一个叙事评论文章.
- 它综合了关于早期肠道微生物组和儿科健康结果的最新研究.
主要成果:
- 肠道微生物组的组成和功能在生命的前三年是动态的.
- 环境暴露可以重编程生命早期的微生物群,影响长期健康.
- 失衡的早期微生物组与几种儿科疾病的风险增加有关.
结论:
- 早期的肠道微生物组是儿童健康和疾病发展的重要因素.
- 准早期的肠道微生物组为预防和管理儿童疾病提供了潜在的治疗策略.
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