术后NSAID使用对旋转手腕修复后阿片类药物消费的影响
Nicholas F Banfield1, Rebekah M Kleinsmith2,3, Adam Hadro2,3
1Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN, USA.
Journal of orthopaedics
|June 13, 2025
概括
在旋转手腕修复后短期服用非类固醇抗炎药物 (NSAIDs) 显著降低了阿片类药物消耗. 这种方法没有对患者的结果或肌愈合产生负面影响,支持NSAIDs在多式联络性疼痛管理中.
科学领域:
- 整形外科手术 整形外科手术
- 疼痛管理 疼痛管理
- 药理学 药理学是指药理学的学科.
背景情况:
- 旋转手腕修复 (RCR) 后的阿片类药物消耗是一个重大问题.
- 非类固醇抗炎药物 (NSAIDs) 建议用于多式疼痛管理,以减少阿片类药物的使用.
- 以前的研究表明,NSAIDs对RCR结果的影响有矛盾的结果.
研究的目的:
- 为了比较接受短时间NSAIDs治疗的接受RCR患者的阿片类药物消耗,与没有接受NSAIDs治疗的患者进行比较.
- 评估NSAIDs对术后疼痛管理和RCR后的临床结果的影响.
主要方法:
- 对125名接受关节镜RCR (2012-2022) 的患者进行了回顾性队列研究.
- 患者被分为两个组:NSAID (6周处方) 和非NSAID.
- 收集关于阿片类药物/NSAID处方,补充,并发症和患者报告结果 (PRO) 的数据.
主要成果:
- 在手术当天,NSAID组的阿片类药物处方显著降低 (306.7MME与1007.4MME相比,p<0.001).
- 在NSAID组中,需要补充阿片类药物的数量较少 (21.6%对37.5%,p = 0.085),尽管在统计学上不显著.
- 两组之间没有观察到功能结果,术后并发症或旋转手套愈合的显著差异.
结论:
- 短时间的NSAIDs有效地减少了RCR后的阿片类药物消费.
- 使用NSAID并没有对功能结果或肌愈合产生不利影响.
- 在RCR患者的多模式疼痛管理协议中应考虑使用NSAID,以减少阿片类药物依赖.
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