在患有口腔状细胞癌的患者中,基因病理特征和临床结果之间的相关性
Shamita Tiwari1, Saurabh Shekhar2, Oruganti V Ramanand3
1Department of Oral and Maxillofacial Surgery, Saraswati Dental College and Hospital, Lucknow, Uttar Pradesh, India.
Journal of pharmacy & bioallied sciences
|June 13, 2025
概括
在口腔状细胞癌 (OSCC) 中,瘤的芽和侵入深度预测了更高的复发率和更差的生存率. 这些组织病理特征对于OSCC的预后和治疗计划至关重要.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 口腔状细胞癌 (OSCC) 是一种常见的癌症.
- 组织病理特征对于预测OSCC患者的结果至关重要.
- 关键指标包括瘤芽,淋巴血管入侵和入侵深度.
研究的目的:
- 研究OSCC患者的特定基因病理参数和临床结果之间的关系.
- 为了确定瘤芽,淋巴血管入侵和入侵深度的预后价值.
主要方法:
- 对OSCC患者数据的回顾性分析.
- 评估瘤芽,入侵深度和淋巴血管入侵.
- 对临床结果的分析,包括复发率和生存率.
主要成果:
- 瘤的芽和侵袭深度与复发率的增加有显著的相关性.
- 这些参数也与OSCC患者的生存结果较差有关.
- 淋巴血管入侵显示出与晚期疾病阶段有很强的联系.
结论:
- 瘤芽和入侵深度是OSCC临床结果的重要预测因素.
- 这些组织病理学特征对于准确的预后和有效的OSCC治疗计划至关重要.
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