甜蜜的盾牌:提高口腔健康与生物活性HETAFU糖果在成年人 - 一个剂量依赖的研究
Sowjanya Lakkoju1, Deepika Bolisetty1,2, Ranjith Kumar1,3
1Consultant Dental Assistant, R&D Department, Lasarkaali Life Sciences PVT Ltd., Hyderabad, Telangana, India.
Journal of pharmacy & bioallied sciences
|June 13, 2025
概括
每天食用5个HETAFU糖果显著减少了有害的口腔细菌,如Streptococcus mutans和Candida,而每天食用2个糖果相比. 这种功能性食品提供了一种剂量依赖的方法来改善口腔微生物组平衡.
科学领域:
- 口腔微生物学 口腔微生物学
- 功能性食品是一种功能性食品.
- 微生物组调制是微生物组的调制.
背景情况:
- 有益生菌和其他生物活性化合物的功能性食品正在探索口腔健康益处.
- HETAFU糖果是一种功能性食品,旨在调节口腔微生物群.
研究的目的:
- 为了比较每天摄入2个和5个HETAFU糖果在8周内对口腔微生物水平的影响.
- 评估HETAFU糖果消费对关键口腔细菌和真菌的剂量依赖影响.
主要方法:
- 一个随机对照试验,有200名参与者分为两个组 (每天2或5个糖果).
- 在基线和2,4,8周时测量了Streptococcus mutans,Lactobacillus,Actinomycetes和Candida的微生物水平.
- 使用Z分数和P值的统计分析确定了微生物变化.
主要成果:
- 这两组都显示出Streptococcus mutans和Candida的显著减少.
- 随着时间的推移,在两组中都观察到乳杆菌和动因菌素的减少.
- 每天食用5个糖果的小组表现出更大的微生物转移,表明口腔微生物组调节的增强.
结论:
- 较高的HETAFU糖果消费 (每天五种) 与中等摄入量 (每天两种) 相比,在减少致病微生物方面提供了更好的好处.
- 存在剂量依赖的关系,增加HETAFU糖果摄入量提供了对口腔微生物失衡的额外保护作用.
- HETAFU糖果显示,作为传统口腔卫生实践的补充,它们具有前景.
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