微生物学见解和诊断方法在内分期病变的内分期病变
Ranjana Kumari1, Bansariben Suhagia2, R Maheshwari3
1BDS, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh, India.
Journal of pharmacy & bioallied sciences
|June 13, 2025
概括
末期病变具有明显的微生物特征. 像PCR和NGS这样的先进诊断改善了这些复杂的口腔感染的分化和管理,从而导致更好的治疗结果.
科学领域:
- 口腔微生物学 口腔微生物学
- 传染性疾病 传染性疾病
- 牙科诊断 牙科诊断 牙科诊断
背景情况:
- 末期病变涉及同时发生的内牙和牙周感染.
- 这些复杂的疾病带来了诊断和治疗方面的挑战.
- 叠加的微生物病因和解剖学的相互通信使管理变得复杂.
研究的目的:
- 研究内分期病变的微生物组成.
- 评估诊断方法,以区分病变类型.
- 改善内分泌期内病变的管理策略.
主要方法:
- 120名患有内分期病变的患者的横截面研究.
- 在根管和牙周样本上使用培养,PCR和NGS进行微生物分析.
- 评估放射成像,临床参数和微生物测试;统计分析.
主要成果:
- 针对初级内牙,牙周和组合病变,确定了不同的微生物概况.
- 与传统方法相比,PCR和NGS显示出更高的灵敏度 (90%) 和特异性 (85%).
- 在不同类型的病变中观察到微生物数量和诊断准确性的显著差异 (P < 0.05).
结论:
- 末期病变具有独特的微生物生态系统,需要精确的诊断.
- 将先进的微生物诊断与临床发现相结合,可以提高病变的分类.
- 改进的分类导致内分期病变的治疗结果更好.
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