一篇关于口腔状细胞癌的叙事评论
Shrikanth Muralidharan1, Monali Nikalje2, Tulsi Subramaniam2
1Department of Research, NIN, Pune Maharashtra, India.
Journal of pharmacy & bioallied sciences
|June 13, 2025
概括
口腔状细胞癌 (OSCC) 是一种常见的口腔癌,通常是晚诊断的. 提高早期检测和精准医学是改善患者生存率和生活质量的关键.
科学领域:
- 在瘤学瘤学.
- 癌症生物学 癌症生物学
背景情况:
- 口腔状细胞癌 (OSCC) 约占口腔恶性瘤的90%,构成了全球健康的重大挑战.
- 高发病率和死亡率与OSCC有关,尽管目前的诊断进步,但经常在晚期诊断.
研究的目的:
- 审查口腔状细胞癌 (OSCC) 的现状,包括其驱动因素,诊断挑战和治疗策略.
- 强调在管理OSCC时需要改进早期检测,新生物标志物和精准医学.
主要方法:
- 对OSCC病原,诊断和治疗的文献综述.
- 对推动OSCC进展的遗传和分子变化的分析,如TP53突变和EGFR过度表达.
- 评估当前和新兴的治疗方式,包括手术,放射治疗,化疗,向治疗和免疫治疗.
主要成果:
- OSCC的特点是基因变化和失调的途径,有助于瘤的进展.
- 现有的诊断工具有局限性,往往导致晚期诊断.
- 新兴疗法显示出希望,但复发和耐药性等挑战仍然存在.
结论:
- 改善OSCC的早期检测策略至关重要.
- 识别新的生物标志物和实施精准医学对于更好的患者结果至关重要.
- 解决治疗耐药性和转移对于提高OSCC患者的生存率和生活质量至关重要.
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