在使用荷尔蒙避孕药的妇女中,压力的主观,行为和生理相关性
Zoé Bürger1,2, Charlotte Kordowich1, Julia Kübbeler1
1Department of Psychiatry and Psychotherapy, Tübingen Center for Mental Health (TüCMH), University of Tübingen, Tübingen, Germany.
概括
激素宫内器械 (IUD) 和口服避孕药 (OC) 明显影响女性的应激反应. 宫内节育器使用者经历了更高的情绪反应,而OCs会使皮质醇水平减弱,影响心理健康.
科学领域:
- 精神内分泌学精神内分泌学
- 神经内分泌学神经内分泌学
- 妇女健康 妇女健康
背景情况:
- 压力是心理健康问题的重要危险因素.
- 从月经周期和口服避孕药 (OCs) 的荷尔蒙波动影响压力水平.
- 有限的研究存在于激素宫内器械 (IUD) 对应激反应的影响.
研究的目的:
- 为了研究使用IUD,OC和具有自然月经周期 (NC) 的女性的精神内分泌应激反应.
- 了解内源性和外源性激素如何影响不同避孕药使用群体的压力.
- 为了比较IUD使用者,OC使用者和NC女性之间的压力相关性.
主要方法:
- 使用重复测量设计来评估应激反应.
- 马斯特里赫特急性压力任务被用来评估主观,内分泌和生理压力相关性.
- 在4个月内通过生态瞬间评估收集了详细的荷尔蒙特征和日常情绪.
主要成果:
- 压力诱导在所有参与者群体中都是成功的.
- 与NC女性相比,IUD使用者报告主观压力和负面影响更高.
- OC使用者表现出皮质醇反应减弱和心率升高,雌激素和孕激素水平降低.
结论:
- 荷尔蒙IUD和OC使用不同影响应激反应机制.
- 避孕套使用者在实验室和日常生活环境中都对压力表现出更高的情绪反应.
- 这些发现强调了外源性激素对女性心理健康和压力调节的全身影响.
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