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Updated: Jun 14, 2025

Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
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设计,合成,生物评估和计算研究的Pyrazine-1,3,4-Oxadiazole类似物作为潜在的抗结核剂

Asha Ganesh Suryawanshi1,2, Chandni Pathak2, Pratik Khona3

  • 1Department of Pharmaceutical Chemistry, Shri. D. D. Vispute College of Pharmacy and Research Centre, New Panvel East, Navi Mumbai, Maharashtra, India.

Chemistry & biodiversity
|June 13, 2025
PubMed
概括

新型皮拉-氧迪亚醇化合物对Mycobacterium tuberculosis (Mtb) 具有强烈的活性. 化合物2f与DprE1酶具有强烈的结合,这表明可能开发新的结核病 (TB) 药物.

关键词:
这是抗结核的抗结核药物.分子对接的分子对接.氧沙醇是一种氧沙醇.皮拉辛 (Pyrazine) 是一种酸盐.综合合成是一种合成.

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