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Preparation of Samples for Electron Microscopy01:20

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To be visualized by an electron microscope, either transmission or scanning, biological samples need to be fixed (stabilized) so the electron beam does not destroy them and dried thoroughly (desiccated/dehydrated) so the vacuum does not affect them. Fixation needs to be done as quickly as possible because the sample properties will start changing as soon as it is removed from its natural environment. For example, in a tissue sample, the oxygen levels begin decreasing, causing an altered...
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Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a...
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Fabrication of Fine Electrodes on the Tip of Hypodermic Needle Using Photoresist Spray Coating and Flexible Photomask for Biomedical Applications
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咖啡环效应诱导液体金属对高分辨率可拉伸生物电极的选择性湿.

Jianhui Chen1, Gongwei Tian2,3, Dan Yang1

  • 1MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, National and Local Joint Engineering Laboratory for Synthesis Transformation and Separation of Extreme Environmental Nutrients, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.

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研究人员开发了高分辨率的多通道液态金属 (LM) 生物电极,用于可伸缩电子产品. 这种新的方法克服了LM表面能量挑战,使生物传感和灵活设备的先进应用成为可能.

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农业NP的产品是什么咖啡环效应的咖啡环效应高分辨率的生物电极液体金属是一种液体金属.可伸缩的电极电极可以伸缩.

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科学领域:

  • 材料科学 材料科学 材料科学
  • 生物电子学 生物电子学
  • 纳米技术 纳米技术

背景情况:

  • 由于其导电性和可变形性,液体金属 (LM) 为可伸缩生物电子设备提供了前景.
  • LM 的高表面能量阻碍了制造高分辨率的多通道生物电极.

研究的目的:

  • 开发高分辨率 (10微米) 和多通道 (16通道) LM生物电极.
  • 为了克服与LM表面能量相关的制造挑战,用于先进的生物电子应用.

主要方法:

  • 使用咖啡环效应引导LM的对齐的银纳米粒子 (AgNP).
  • 在Ag NP上利用LM的选择性湿,以精确的电极图案.
  • 用导电性离子凝封装的记录站点来降低阻抗.

主要成果:

  • 实现了高分辨率 (10微米) 和多通道 (16通道) LM生物电极阵列.
  • 证明了出色的拉力导电性 (600%应变) 和周期性稳定性 (10,000个周期在100%应变).
  • 将接口阻抗降低到4.14kΩ (1kHz),并确保了35天的电极稳定性.

结论:

  • 该研究提出了制造高分辨率,可拉伸LM电极的可行策略.
  • 开发的生物电极能够获得高质量的电生理信号.
  • 在人类运动检测,手写识别和朱尔加热方面的成功应用突显了它们在灵活电子方面的潜力.