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Updated: Jun 16, 2025

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
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In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells

Published on: January 20, 2019

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EZH2突变增加了淋巴瘤中染色质状态的异质性

Daniel Holoch1, Raphaël Margueron1

  • 1Institut Curie, INSERM U934/CNRS UMR 3215, Paris Sciences et Lettres Research University, Sorbonne University, Paris, France.

PLoS biology
|June 13, 2025
PubMed
概括

在EZH2中获得功能的突变对B细胞淋巴瘤中的染色质状态产生了深刻的改变. 这种重编程增加了细胞间的变异性,为淋巴瘤的发展提供了新的见解.

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