尽管有生化控制,但在患有前乳腺瘤的患者中微妙的认知障碍和心理投诉
Victoria R van Trigt1, Cornelie D Andela1,2, Leontine E H Bakker1
1Department of Medicine, Division of Endocrinology, and Center for Endocrine Tumors Leiden, Leiden University Medical Center, Leiden, the Netherlands.
The Journal of clinical endocrinology and metabolism
|June 13, 2025
概括
患有前乳腺瘤的患者,即使经过生物化学控制,也会在记忆,注意力和处理速度方面经历微妙的认知障碍. 他们还报告了诸如冷漠和焦虑之类的心理问题增加,需要医生意识和干预.
科学领域:
- 神经内分泌学神经内分泌学
- 认知神经科学 认知神经科学
- 临床心理学 临床心理学
背景情况:
- 益生菌瘤是一种常见的垂体瘤,通常用多巴胺激动剂或手术治疗.
- 益生菌瘤的生物化学控制旨在使益生菌素水平正常化,但可能无法完全解决患者的症状.
- 治疗前乳腺瘤的长期认知和心理影响尚不清楚.
研究的目的:
- 为了评估生化控制的益生菌瘤患者的认知功能.
- 为了评估生化控制的益生菌瘤患者的心理投诉.
- 为了比较治疗前乳腺瘤患者和匹配的对照组之间的认知和心理结果.
主要方法:
- 采用了横截面研究设计,将前乳腺瘤患者与年龄,性别和教育匹配的对照患者进行比较.
- 用八项标准化测试来评估认知功能,这些测试涵盖了记忆,语言流,处理速度,注意力和执行功能.
- 用七个经过验证的调查问卷评估情绪,冷漠,易怒和疲劳来评估心理健康.
主要成果:
- 与对照组相比,患有益生菌瘤的患者表现出明显的口头记忆,选择性注意力和处理速度的缺陷.
- 甲状腺瘤患者报告了较高水平的冷漠,易怒,疲劳,焦虑和抑郁症状.
- 在执行功能或组之间的任务切换能力方面没有观察到显著差异.
结论:
- 生物化学控制的乳腺瘤与微妙但显著的认知障碍和增加的心理痛苦有关.
- 这些发现强调了监测前性瘤患者的认知和心理健康的重要性.
- 医疗保健提供者应该主动解决这些非荷尔蒙后续在益生菌瘤管理.
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