保护基底时语言区域:在主导时叶切除术后预测口头记忆结果的范式转变
Olivier Aron1, Judith Mercier2, Natacha Forthoffer2
1Neurology Department, CHRU Nancy, Lorraine University, Nancy, France; IMoPA, Lorraine University, CNRS, F-54000, Nancy, France.
概括
在手术期间切割基底时间语言区域 (BTLA) 显著影响口语记忆. 精确的BTLA映射对于预测和最大限度地减少前叶切除术后的长期认知衰退至关重要.
科学领域:
- 神经科学是一个神经科学.
- 认知神经学 认知神经学
- 手术 手术 手术
背景情况:
- 药物耐药的标准前叶切除术 (aTL) 有不可预测的认知结果.
- 基底时语言区域 (BTLA) 的切除是已知的aTL后语言障碍的预测指标.
研究的目的:
- 调查基底时语言区域 (BTLA) 切除对口头记忆 (VM) 结果的具体影响.
- 评估手术后BTLA切除程度与口头记忆下降之间的相关性.
主要方法:
- 使用SEEG电极对21名接受针对主导半球的定制aTL患者的BTLA进行映射.
- 量化了BTLA切除程度,并使用延迟回忆测试评估了术后早期和晚期的口头记忆.
主要成果:
- 在BTLA切除程度和口头记忆的下降之间发现了显著的相关性,无论是早期还是晚期.
- 虽然整体腹腔皮切除影响了早期记忆,但只有BTLA切除预测了长期口语记忆障碍.
结论:
- 在BTLA中,BTLA在词汇访问和声明记忆中发挥作用.
- 个性化的BTLA映射对于预测和缓解手术中长期认知缺陷至关重要.
关键词:
前側葉切除術 前側葉切除術基本时语言区域的语言区域.药物耐药的叶发症电动皮质刺激是一种电动皮质刺激.立体电脑脑摄影 (Stereo-electroencephalography) 是一种立体电脑摄影技术.腹腔皮层的时间皮层.语言记忆 语言记忆更多相关视频
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