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模拟喉病理中的复杂关系:沙特阿拉伯患者听力障碍的结构方程分析
Omar Ibrahim Alanazi1, Sameer Al-Bahkaly2, Feras Alkholaiwi3
1College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; Division of Otolaryngology - Head and Neck Surgery, King Abdullah Specialized Children's Hospital, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia; King Abdullah International Medical Research Center (KAIMRC), Riyadh, Saudi Arabia; Chief Executive Officer, KliniKa SA, Riyadh, Saudi Arabia.
女性性别,年龄,吸烟和语音使用等音障风险因素与特定的喉病理有关. 这项研究模拟了这些联系,以确定有针对性的干预措施的高风险群体和进展模式.
科学领域:
- 喉腔病理学 喉腔病理学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 听力障碍是影响沟通和生活质量的常见疾病.
- 了解风险因素和喉病理之间的相互作用至关重要,但往往缺乏结构化建模.
- 以前的研究还没有完全阐明导致失声症的复杂相互作用.
研究的目的:
- 通过结构方程建模 (SEM) 研究将人口和行为风险因素与特定喉病理联系起来的直接和间接途径.
- 在沙特人口中确定风险因素与结构性,炎症性,神经和功能性喉病理的流行之间的显著关联.
- 开发一个综合性听力障碍病因学模型,为有针对性的查和预防策略提供信息.
主要方法:
- 一项回顾性队列研究分析了沙特阿拉伯利雅得一家三级医院998名听障患者的数据.
- 喉病理被分为结构性,炎症性,神经性和功能性类别.
- 使用结构方程建模 (SEM) 来评估直接和间接途径,包括交叉病理联系和调节效应.
主要成果:
- 结构性病理是最常见的 (33.9%).
- 女性性别显著预测了结构和功能病理.
- 年龄的增加与炎症,神经和功能病理有关.
- 吸烟强烈预测炎症病理,而职业语音使用预测结构和功能病理.
结论:
- 基于SEM的模型揭示了沙特人口中具有明显的人口统计学关联的显著失声路径.
- 确定的高风险群体包括女性声乐专业人士和老年吸烟者.
- 这些发现突出了进展模式,如炎症至神经系统和结构至功能病理,有助于风险分析和有针对性的干预措施.
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