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微/纳米电机作为气体治疗的平台

Shuangjiao Sun¹, Ya Liu¹, Shuhuai Wang¹

¹State Key Laboratory of Advanced Medical Materials and Devices, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Tianjin Institutes of Health Science, Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300192, China.

|June 13, 2025

概括

微/纳米发动机 (MNM) 为治疗性气体输送提供了先进的解决方案. 这些智能纳米材料能够精确控制气体释放,以有效治疗疾病和调节微环境.

科学领域:

生物医学工程生物医学工程
纳米技术纳米技术
治疗性气体输送治疗性气体输送

背景情况:

治疗气体的积极输送对于疾病干预至关重要,但在向输送和控制释放方面面临挑战.
基于纳米材料的系统,特别是微/纳米电机 (MNM),显示出克服这些局限性的前景.

研究的目的:

综合审查使用MNM用于精确的治疗气体输送和治疗的最新进展.
突出MNM在调节生物微环境治疗疾病方面的潜力.

主要方法:

对人工MNM的各种概念验证设计进行讨论.
分析生物环境中的MNM推进和对刺激有反应的气体释放机制.
对NO,H2S,CO,O2和H2等治疗气体的生理功能进行审查.

主要成果:

可以设计MNM以实现高效的推进和治疗气体的有针对性的输送.
智能MNM在对内在或外在刺激的反应中展示了受控的气体释放.
在疾病治疗中,MNM显示了微环境调制的巨大潜力.

结论:

MNM代表了一个有前途的移动平台,用于精确的气体输送和治疗.
预计MNM的进一步发展将导致用于气体治疗的复杂输送系统.
确定了当前气体治疗MNM技术的挑战和局限性.

关键词:

积极的交付活动交付.生物医学应用程序有控制释放的释放.气体疗法是一种治疗方法.微型/纳米发动机的使用

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Gas Exchange and Transport

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Gas exchange, the intake of molecular oxygen (O2) from the environment and the outflow of carbon dioxide (CO2) into the environment, is necessary for cellular function. Gas exchange during respiration occurs largely via the movement of gas molecules along pressure gradients. Gas travels from areas of higher partial pressure to areas of lower partial pressure. In mammals, gas exchange occurs in the alveoli of the lungs, which are adjacent to capillaries and share a membrane with them.