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Updated: Jun 16, 2025

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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从潜在的药物点到遗传风险因素解码大动脉剖析:一项门德尔随机化研究

Jiaqi Hou1, Lihua Lin1, Jing Huang1

  • 1Department of Forensic Medicine, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.

European journal of pharmacology
|June 13, 2025
PubMed
概括

这项研究确定了五种用于大动脉解剖 (AD) 的新型药物标,这是一个缺乏有效治疗的致命疾病. 这些发现可能有助于预测AD和开发新疗法.

关键词:
动脉剖析是一个大动脉剖析.目标药物是药物目标.遗传学 遗传学 是一个门德尔的随机化分子对接是分子对接.风险因素 风险因素

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相关概念视频

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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