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在早期随机临床试验中估计治疗效果,这些试验涉及多个数据源,用于外部控制

Heiko Götte1, Marietta Kirchner2, Meinhard Kieser2

  • 1Clinical Measurement Sciences, Merck Healthcare KGaA, Darmstadt, Germany.

Journal of biopharmaceutical statistics
|June 13, 2025
PubMed
概括

使用多个外部数据源的增强随机临床试验可以提高早期阶段试验的精度. 仔细选择数据和分析方法至关重要,以减轻潜在的偏差,并确保可靠的治疗效果估计.

关键词:
估计 估计 估计增强的RCT是一种增强RCT.外部控制器是外部控制器.多个数据源多个数据源.时间到事件数据.

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