持续的对称白质超强度:一个案例报告
S A Paranavitane1, P Manokaran2, N T Wijesinghe2
1Institute of Neurology, National Hospital of Sri Lanka, Colombo, Sri Lanka. shiran_p@live.com.
Journal of medical case reports
|June 13, 2025
概括
异常罕见的脑瘤 - - 形性星细胞瘤,在MRI上异常可能导致持续的对称白质超强度. 这个案例突出了这种罕见的中枢神经系统瘤的呈现.
科学领域:
- 神经瘤学神经瘤学
- 神经辐射学神经辐射学
- 神经病理学神经病理学
背景情况:
- 白质超强度 (WMH) 是磁共振成像 (MRI) 的常见发现.
- 然而,由形性星细胞瘤引起的WMH是一种主要的中枢神经系统瘤,是一种不寻常的呈现.
研究的目的:
- 报告一种异常的形性星细胞瘤病例,呈现出广泛的对称白质超强度.
主要方法:
- 一个22岁的男性的一个案例研究,一个月的头痛,改变了意识,意识下降.
- 诊断工作包括脑部的计算机断层扫描 (CT) 和磁共振成像 (MRI),脑脊液 (CSF) 分析和腹腔壁活检.
- 治疗包括外腔室排水,静脉注射液体,德克萨米他,塞夫和阿西克洛维尔,随后转诊进行瘤管理.
主要成果:
- 核磁共振扫描显示了白质和小脑半球中广泛的,对称的T2和流体减弱的反转恢复 (FLAIR) 超强度.
- 最初的治疗和CSF分析没有显示出显著的改善或可识别的感染.
- 腹腔壁活检证实了阿纳普拉斯细胞瘤 (世卫组织三级).
结论:
- 这一案例强调了在不同寻常的白质异常的差异诊断中考虑初级中枢神经系统瘤的重要性.
- 无塑性星细胞瘤可以在MRI上呈现异常,持续,对称的白质超强度.
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