开发和外部验证用于预测灵活尿路透镜后败血症的诺米克图
Sheng-Shan Liu1, Da-Qing Zhu2, Jun-Tao Tan3
1Department of Nephrology, Nanchang People's Hospital, Nanchang, China.
European journal of medical research
|June 13, 2025
概括
一种新的诺米图准确地预测了结石在柔性尿道透视术 (FURS) 后的败血症风险. 该工具有助于临床医生识别高风险患者,以便及时干预并改善结果.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 医疗信息学 医疗信息学
背景情况:
- 柔性尿道透视 (FURS) 是治疗上尿路结石的常见手术.
- 手术后败血症是FURS后的一个严重并发症.
- 需要预测工具来减轻败血症风险.
研究的目的:
- 开发和外部验证用于预测FURS后败血症风险的诺米克图.
- 确定FURS患者手术后败血症的关键预测因素.
主要方法:
- 这是一项多中心的,追溯的观察性队列研究,对1722名接受FURS.的患者进行了观察.
- 多变量逻辑回归分析以确定独立预测因素.
- 开发和验证一个预测名ogram.
主要成果:
- 确定了六个独立的预测因素:女性性别,阳性尿液培养,大石头大小 (≥2厘米),鹿角石头,低白蛋白 (<35 g/L) 和长时间的手术时间 (≥60 分钟).
- 诺米图表表现出极好的预测性能,具有高的C指数值 (0.88培训,0.87内部验证,0.85外部验证).
- 通过决策曲线分析证实了强大的校准和临床效用.
结论:
- 经过验证的血红图提供了一个简单而准确的工具,用于预测FURS后的败血症风险.
- 诺姆图可以帮助临床医生进行早期干预和患者管理.
- 建议在更大的队列中进一步验证.
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