一个回顾性病例控制研究,评估与单一退伍军人事务医疗中心住院患者相关的药物
Emma Stragand1, Jennifer Armbrust1, Jiahui Chen1
1Robley Rex Veterans Affairs Medical Center, Louisville, Kentucky.
The Senior care pharmacist
|June 14, 2025
概括
某些药物,包括抗精神病药物和非镇静性抗抑郁药,与老年人住院患者跌倒的增加有关. 这一发现突显了老年患者潜在的药物风险,并为预防跌倒策略提供了信息.
科学领域:
- 老年医学 老年医学
- 药理学 药理学是指药理学的学科.
- 患者安全 患者安全
背景情况:
- 老年人的跌倒会导致严重的健康问题,包括骨折和头部受伤.
- 住院患者的跌倒在很大程度上导致医疗保健成本增加和住院时间延长.
- 尽管确定了风险因素,但住院患者的跌倒仍然是医疗保健机构的持续挑战.
研究的目的:
- 为了确定与老年患者住院倒相关的特定药物.
- 为了比较失败者与非失败者匹配的对照组的药物治疗概况.
- 调查与退伍军人事务医疗中心 (VAMC) 内的跌倒的药物相关风险.
主要方法:
- 进行了一项单中心,回顾性,病例控制研究.
- 分析了65岁以上的患者,入院时间≥48小时 (不包括ICU/宿舍).
- 根据年龄,性别,停留时间和服务类型,跌倒患者与非跌倒者进行了1:1匹配.
主要成果:
- 抗精神病药物,非镇静性抗抑郁药和费纳斯特与跌倒的相关性更高.
- 跌倒史和尿失禁是与跌倒相关的重大并发症.
- 统计学意义 (P值) 证实了这些因素与住院患者跌倒的相关性.
结论:
- 抗精神病药物和非镇静性抗抑郁药的使用与住院患者跌倒的风险增加有关.
- 这些发现强调了药物审查对于老年住院患者的跌倒预防的重要性.
- 建议对更大,更多样化的群体进行进一步的研究,以验证这些与药物相关的跌倒风险.
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