在随机对照试验中,对运动训练对阿斯素影响的系统审查和元分析
Mohammad Rahman Rahimi1, Michael E Symonds2, Hassan Faraji3
1Department of Exercise Physiology, University of Kurdistan, Sanandaj, Iran.
Physiological reports
|June 14, 2025
概括
运动训练显著降低了阿斯素水平,阿斯素是一种与胰岛素抵抗和代谢障碍相关的蛋白质. 这一发现表明,运动可能是管理肥胖和相关疾病的关键干预措施.
科学领域:
- 代谢健康 代谢健康
- 内分泌学 在内分泌学.
- 运动生理学 运动生理学
背景情况:
- 一种蛋白质阿斯素与胰岛素抵抗,肝脏葡萄糖分泌,肥胖,代谢障碍和心血管疾病有关.
- 升高的阿斯素水平与不良的代谢和心血管结果有关.
- 了解调节阿斯素的因素对于开发治疗策略至关重要.
研究的目的:
- 系统地审查和元分析运动训练 (ET) 对循环阿斯素度的影响.
- 评估不同运动方式在降低阿斯素水平方面的有效性.
- 探索潜在的调节者影响ET和asprosin之间的关系.
主要方法:
- 在PubMed,Web of Science和Google Scholar系统搜索随机对照试验 (2016年1月至2024年11月).
- 纳入标准侧重于研究人群,干预 (ET) 和研究类型.
- 使用综合元分析软件 (CMA2) 进行的元分析,随机效应模型和Hedges' g用于效应大小计算.
主要成果:
- 在运动训练中观察到阿斯素度的总体显著下降 (Hedges' g = -1.70,p < 0.0001).
- 有氧训练,HIIT和抵抗训练都显示了阿斯素的显著减少.
- 亚组分析表明,根据体重指数和健康状况,阿斯素减少的显著差异,但不是性别,训练类型或持续时间.
结论:
- 运动训练有效地降低了循环中的阿斯素水平.
- 与ET一起观察到的阿斯素的减少可能有助于改善代谢健康和预防与肥胖相关的疾病.
- 进一步的研究可以阐明精确的机制,并优化对阿斯素调节的运动干预措施.
更多相关视频
12:59Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
Published on: July 5, 2017
12.6K
04:23Author Spotlight: Using a Rabbit Model to Explore the Efficacy of Tuina in Treating Knee Osteoarthritis
Published on: August 25, 2023
1.4K
相关概念视频
01:20Exercise and Cardiovascular Response
751
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
751
01:27Exercise and Muscle Performance
1.4K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
1.4K