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基于微板的酶活性测定协议,由基于活动的探头提供动力

Exequiel O J Porta1, Karunakaran Kalesh2,3, Jaime A Isern4

  • 1Department of Chemistry, Durham University, Durham, UK. e.porta@ucl.ac.uk.

Methods in molecular biology (Clifton, N.J.)
|June 14, 2025
PubMed
概括

这项研究引入了一种新的方法,将基于活性的蛋白质分析 (ABPP) 与微板测试相结合,以快速发现酶抑制剂. 这种方法通过有效地选化合物库对目标酶的检测,加快了潜在药物候选物的识别和表征.

关键词:
基于活动的探头.基于活动的蛋白质简介.化学探头 化学探头药物发现 药物发现 药物发现抑制剂是一种抑制剂.微板的微板是什么意思基于板块的测试方法查检查 查检查 查检查

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