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Updated: Apr 23, 2026

Profiling of Methyltransferases and Other S-adenosyl-L-homocysteine-binding Proteins by Capture Compound Mass Spectrometry CCMS
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从组织蛋白质组中对反应性核性氨酸位点进行基于活动的分析,用于药物发现应用

Hasini Kalpage1, An Chi2, Smaranda Bodea3

  • 1Merck & Co., Inc., Boston, MA, USA.

Methods in molecular biology (Clifton, N.J.)
|June 14, 2025
PubMed
概括

这项研究提出了一种新的方法,用于识别蛋白质中的反应性氨酸位,使用低输入样本. 该技术能够在各种生物环境中对共价药物标进行详细的分析,这对于药物发现至关重要.

关键词:
共价的小分子分子.药物发现 药物发现高通量的高通量.质谱测量质量谱测量TMTpro TMTpro 是一个专业的项目.组织蛋白质组是组织的蛋白质组.

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Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
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