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Updated: Jul 10, 2026

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在成都献血者中,对D变异的血清分析和分子特征分析

Jue Hou1, Yu Xia1, Jian Li1

  • 1Blood grouping reference laboratory, Chengdu blood center, Sichuan, China.

Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
|June 14, 2025
PubMed
概括

精确的RhD类型对输血安全至关重要. 这项研究在成都的献血者中发现了多种多样的D变异,为中国人群制定了定制的RHD基因定型策略,以防止抗D免疫接种.

关键词:
D 变种 D 变种在RHD等位基因中.通过RHD基因型鉴定.血清学分析分析 血清学分析

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Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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