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相关概念视频

Olfaction01:25

Olfaction

44.3K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
44.3K
Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

8.2K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
8.2K
Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

9.1K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
9.1K

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相关实验视频

Updated: Jun 16, 2025

Imaging Odor-Evoked Activities in the Mouse Olfactory Bulb using Optical Reflectance and Autofluorescence Signals
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Imaging Odor-Evoked Activities in the Mouse Olfactory Bulb using Optical Reflectance and Autofluorescence Signals

Published on: October 31, 2011

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气味编码通过微妙的时间尺度尖峰同步模式在嗅觉灯泡的气味.

Jesse C Werth1, Matthew Einhorn1, Thomas A Cleland1

  • 1Dept. Psychology, Cornell University, Ithaca, NY 14853, USA.

Journal of neurophysiology
|June 14, 2025
PubMed
概括

嗅觉灯泡的马振荡同步特定的神经元群体,编码气味质量,而不是度. 这种尖峰计时机制允许度不变的气味信息传输.

科学领域:

  • 神经科学是一个神经科学.
  • 嗅觉系统研究研究 嗅觉系统研究
  • 神经振荡是一种神经振荡.

背景情况:

  • 哺乳动物的嗅觉灯泡 (OB) 在气味采样过程中产生内源性马振荡.
  • 这些振荡涉及神经电路动力学和毫秒时间尺度峰值时间约束.
  • 在气味表现中OB马振荡的作用仍然不清楚.

研究的目的:

  • 为了调查马时间尺度尖峰同步是否是特定于气味和可复制的.
  • 为了确定spike-timing指标是否执行额外的信号处理.
  • 了解OB神经动力学如何编码气味信息.

主要方法:

  • 使用了OB片段录音.
  • 采用光遗传刺激,通过对嗅觉感官神经元树木的模式刺激来产生"虚构的气味".
  • 分析了尖峰时间动态和同步模式.

主要成果:

  • 一个强烈相锁定以唤起马振荡的 mitra/tufted 细胞的子集.
  • 这些细胞在马时间尺度上表现出紧密结合的尖峰-尖峰同步.
  • 同步的神经元群体编码虚构的气味质量,而不是度,并且在整个试验中得到保护.
关键词:
马振荡的马振荡多电极阵列是一个多电极阵列.视觉遗传学 视觉遗传学切片电生理学 切片电生理学尖尖的时间表.

更多相关视频

Recording Temperature-induced Neuronal Activity through Monitoring Calcium Changes in the Olfactory Bulb of Xenopus laevis
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Recording Temperature-induced Neuronal Activity through Monitoring Calcium Changes in the Olfactory Bulb of Xenopus laevis

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The Olfactory System as a Model to Study Axonal Growth Patterns and Morphology In Vivo
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The Olfactory System as a Model to Study Axonal Growth Patterns and Morphology In Vivo

Published on: October 30, 2014

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相关实验视频

Last Updated: Jun 16, 2025

Imaging Odor-Evoked Activities in the Mouse Olfactory Bulb using Optical Reflectance and Autofluorescence Signals
08:30

Imaging Odor-Evoked Activities in the Mouse Olfactory Bulb using Optical Reflectance and Autofluorescence Signals

Published on: October 31, 2011

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Recording Temperature-induced Neuronal Activity through Monitoring Calcium Changes in the Olfactory Bulb of Xenopus laevis
11:08

Recording Temperature-induced Neuronal Activity through Monitoring Calcium Changes in the Olfactory Bulb of Xenopus laevis

Published on: June 3, 2016

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The Olfactory System as a Model to Study Axonal Growth Patterns and Morphology In Vivo
08:29

The Olfactory System as a Model to Study Axonal Growth Patterns and Morphology In Vivo

Published on: October 30, 2014

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结论:

  • OB马时间尺度尖峰同步是编码和输出气味信息的度不变机制.
  • 这种时间编码对于皮质状皮质的处理至关重要.
  • 非同步的尖峰不太可能有助于整体气味表示.