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Updated: Jun 16, 2025

Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons
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Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons

Published on: August 6, 2014

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光RNA:药物发现的新机遇

Fangting Zuo1, Ziheng Gao1, Xianjun Chen1

  • 1Optogenetics & Synthetic Biology Interdisciplinary Research Center, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China; Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, School of Pharmacy, East China University of Science and Technology, Shanghai, China.

Trends in pharmacological sciences
|June 14, 2025
PubMed
概括

光RNA (FRs) 和FR衍生生物传感器 (FRBs) 提供了追踪RNA动态和帮助药物发现的新方法. 本综述探讨了它们在加速RNA和小分子药物开发中的应用.

关键词:
FR衍生生物传感器生物传感器在RNA药物RNA药物中.发现药物的发现.光RNA是一种光RNA.小分子药物的药物.

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Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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