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Updated: May 11, 2026

Using Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells for Drug Discovery
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提高肝病临床试验的效率:一个安全的,大型的语言模型驱动的预选管道

Xiongbin Gui1, Hanlin Lv2, Xiao Wang2

  • 1The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, 530023, China.

BioData mining
|June 14, 2025
PubMed
概括

一个新的AI管道准确地选患者进行肝病临床试验,提高效率和数据安全性. 这种方法可以提高治疗肝细胞癌和肝硬化等复杂疾病的患者招募率.

关键词:
电子健康记录是电子健康记录.资格标准 资格标准肝脏疾病是一种肝脏疾病.自然语言处理自然语言处理.患者招募 患者招募

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Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
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Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
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