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在COPD中,HIF-1α通过激活REDD1来保护香烟诱导的呼吸道上皮细胞亡

Jianlan Hua1, Li Liu1, Binfeng He2

  • 1Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

International immunopharmacology
|June 15, 2025
PubMed
概括

缺氧诱导因子1-α (HIF-1α) 保护慢性阻塞性肺病 (COPD) 的呼吸道上皮细胞亡. 它的下游效应剂REDD1抑制了细胞亡,这表明它是COPD的治疗标.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.慢性慢性肺炎是一种慢性慢性肺炎,COPD是一种慢性肺炎.香烟烟雾的烟雾是什么意思这就是HIF-1α.在REDD1中,REDD1是指REDD1.

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