在头部和部手术中术后血糖控制
Sara Kring Nielsen1, Josefine Qvortrup Olsen1, Mahsa Jalili1
1Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.
Clinical nutrition ESPEN
|June 15, 2025
概括
在手术前的德克萨米他并没有显著恶化头手术患者的术后血糖控制. 虽然发生过高血糖症,但可以用胰岛素治疗,这表明标准方案可能不必使用.
科学领域:
- 麻醉学 麻醉学
- 内分泌学 在内分泌学.
- 术后恢复 术后恢复
背景情况:
- 手术前使用德克萨米他来预防手术后的疼痛和恶心.
- 它对手术后血糖控制和恢复的影响需要进一步调查.
- 临床试验的注册:NCT04021186.6. 临床试验的注册:NCT04021186.
研究的目的:
- 为了研究手术前德克萨米他对手术后血糖控制的影响.
- 评估血糖控制对头手术后患者康复的影响.
- 评估对治疗术后胰岛素耐药性的标准方案的必要性.
主要方法:
- 在住院头部和部手术患者的随机对照试验.
- 使用Freestyle Libre系统进行持续的葡萄糖监测.
- 干预组接受了胰岛素治疗高血糖症;对照组没有.
主要成果:
- 在54%的患者中观察到高血糖 (血糖≥10 mmol/L).
- 小剂量胰岛素使血糖正常化;注意到p-C-水平升高.
- 两组之间没有最大血糖,住院或再入院的显著差异.
结论:
- 手术后高血糖是常见的,但在头部和部手术患者中可以控制.
- 手术前的德克萨米他没有导致显著的胰岛素耐药性.
- 对高血糖症的标准术后方案可能不适用;建议频繁监测血糖.
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