探索功能激活和幻觉易感之间的联系
Abdullah M Alotaibi1, Manal H Alosaimi2, Razan S Orfali3
1Research Centre, King Fahad Medical City, Riyadh 12231, Saudi Arabia; Department of Experimental Psychology, Liverpool University, Liverpool L69 7ZX, UK.
Brain research bulletin
|June 15, 2025
概括
具有较高幻觉倾向的个体在视觉任务期间在语言区域增加了大脑激活,这表明抑制缺陷. 这项针对健康成年人的功能性MRI (fMRI) 研究揭示了幻觉易感的复杂神经相关性.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
背景情况:
- 幻觉与大脑激活的改变有关,特别是在感官和语言领域.
- 目前的幻觉易感模型缺乏强大的经验支持,需要进一步调查神经相关性.
研究的目的:
- 通过使用功能性MRI (fMRI) 对健康个体幻觉易感的神经基础进行调查.
- 检查幻觉易感得分和听觉和视觉处理任务期间大脑激活之间的关系.
主要方法:
- 健康的大学生在执行听觉和视觉任务时接受了fMRI扫描.
- 参与者完成了修改后的劳内-斯莱德幻觉量表 (LSHS-M),以评估幻觉倾向.
- 分析了与任务相关和无关区域的LSHS得分和大脑激活之间的相关性.
主要成果:
- 在幻觉得分和任务相关大脑区域激活之间没有发现显著的相关性.
- 在视觉任务期间,在与语言相关的区域观察到积极的相关性,这表明在与任务无关的领域有更大的参与.
- 侧面化指数与幻觉得分没有相关性,在非临床样本中挑战了连续性假设.
结论:
- 研究结果表明,在更容易产生幻觉的个体中存在抑制缺陷,这支持了减少认知控制理论.
- 这项研究突出了导致幻觉倾向的复杂神经机制,以及对敏感任务和多样化的群体进行进一步研究的需要.
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