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Updated: Sep 19, 2025

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TREX1激活剂:一种通过cfDNA清除来治疗类风湿性关节炎的新治疗策略

Yuping Wang1, Weidan Luo2, Wanyu Wu3

  • 1Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Faculty of Chinese Medicine, Macau University of Science and Technology, Macao; Department of Breast, Thyroid and Vascular Surgery, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan 646600, China.

Pharmacological research
|June 15, 2025
PubMed
概括

天然化合物丁 (PTE) 和比洛巴利德 (BB) 激活TREX1,清除无细胞DNA (cfDNA),减少类风湿性关节炎 (RA) 的炎症. 这种TREX1激活为RA和其他炎症性疾病提供了一种新的治疗策略.

关键词:
比洛巴利德 (BB) 是一种没有细胞的DNA (cfDNA) 清除.天然化合物是一种自然化合物.聚乙烯 (PTE) 是一种类风湿性关节炎 类风湿性关节炎 类风湿性关节炎这就是TREX1的特点.

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