追踪损失:了解其在科因布拉地区 (2005-2017) 结核病患者中的决定因素
Ricardo Eufrásio1, Maria Celeste Alcobia2, Carlos Robalo Cordeiro3
1Public Health Unit - ACeS Baixo Vouga, 3750-102, Águeda, Portugal.
The Indian journal of tuberculosis
|June 15, 2025
概括
结核病患者失去了随访 (LTFU) 往往是移民或滥用酒精. 优先考虑这些人的重症监护和协调支持服务对于控制结核病至关重要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染病控制和控制传染病
背景情况:
- 结核病 (TB) 传播因患者逃离治疗而加剧.
- 识别失踪后随访 (LTFU) 患者的风险因素对于预防持续的结核病传播至关重要.
研究的目的:
- 评估与结核病患者失去随访 (LTFU) 相关的风险因素.
- 分析2005年至2017年期间在科因布拉地区报告的结核病患者中LTFU的预测因素.
主要方法:
- 一个病例控制研究设计,将LTFU结核病患者 (病例) 与成功治疗的患者 (对照) 进行比较.
- 分析包括社会,人口,并发症,疾病,治疗史,耐药性和经济因素.
- 使用后勤回归来确定LTFU的独立风险因素.
主要成果:
- 两种分析表明,移民,失业,建筑工作和药物滥用 (毒品,酒精,烟草) 与LTFU有关.
- 同时感染艾滋病毒,C型肝炎和B型肝炎病毒也是显著的危险因素.
- 多变量分析确定移民身份和滥用酒精是LTFU最强的预测因素.
结论:
- 成行为和移民身份与结核病患者失去随访的可能性增加密切相关.
- 强化后续护理和加强与心理健康和药物滥用计划的协调是高风险患者的建议.
- 立法措施可能对反抗性患者来说是必要的,特别是在管理多药耐药结核病时.
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