传统中国医学调节下丘脑神经来调节食欲:一个全面的审查
Yuqi Wang1, Fanghua Qi1, Min Li2
1Department of Traditional Chinese Medicine, Shandong Provincial Hospital Affiliated with Shandong First Medical University, Ji'nan, China.
Bioscience trends
|June 15, 2025
概括
传统中医 (TCM) 有效地准下丘脑食欲调节以对抗肥胖. 各种TCM疗法调节关键的神经路径,为代谢障碍提供新的策略.
科学领域:
- 代谢科学 代谢科学
- 神经内分泌学神经内分泌学
- 传统医学的传统医学.
背景情况:
- 肥胖是一种全球健康危机,其驱动力来自能量恒温的破坏.
- 下丘脑通过神经网调节食欲和能量平衡.
- 传统中国医学 (TCM) 在调节食欲调节方面显示出潜力.
研究的目的:
- 系统地审查TCM在影响肥胖的下丘脑神经信号传递方面的机制.
- 评估TCM对调节食欲路径的影响的证据.
主要方法:
- 对PubMed和中国国家知识基础设施数据库的系统审查.
- 专注于影响下丘脑神经信号通路的TCM干预.
- 对AgRP/NPY,POMC/CART神经元和瘦素信号传递的影响分析.
主要成果:
- 不同的TCM模式,包括化合物,配方,提取物和专利药物,影响食欲路径.
- 通过TCM干预,可以调节关键的神经系统,如AgRP/NPY和POMC/CART.
- 有证据支持TCM对能量平衡中瘦素信号的影响.
结论:
- 传统医学干预措施对下丘脑食欲调节机制产生显著影响.
- 这些发现为TCM的抗肥胖性质提供了机械洞察力.
- 将TCM与现代方法相结合,为肥胖提供了新的治疗策略.
相关概念视频
Regulation of Food Intake
539
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
539
Hormonal Regulation
44.7K
Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
44.7K
Regulation of Hormone Secretion
4.2K
Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
Humoral...
Humoral...
4.2K
Diencephalon: Hypothalamus and Coordination
2.2K
The hypothalamus is a small yet highly complex and essential brain region that plays a crucial role in regulating various bodily functions. Anatomically, it is located at the base of the brain, just above the brainstem and below the thalamus, forming part of the limbic system.
The hypothalamus interacts with other brain regions, including the pituitary gland, through a direct physical connection called the hypothalamic-pituitary axis. The hypothalamus receives somatic and visceral inputs and...
The hypothalamus interacts with other brain regions, including the pituitary gland, through a direct physical connection called the hypothalamic-pituitary axis. The hypothalamus receives somatic and visceral inputs and...
2.2K
Primary Motives: Hunger and Thirst
358
Hunger and thirst are fundamental physiological drives crucial for maintaining homeostasis and ensuring the survival of both humans and animals. These drives are regulated through complex interactions between the brain, hormones, and sensory receptors.
Hunger arises when the brain detects changes in the body's nutrient levels, including glucose, lipids, amino acids, and hormones such as ghrelin and leptin. The hypothalamus plays a central role in hunger regulation. The lateral hypothalamus...
Hunger arises when the brain detects changes in the body's nutrient levels, including glucose, lipids, amino acids, and hormones such as ghrelin and leptin. The hypothalamus plays a central role in hunger regulation. The lateral hypothalamus...
358


