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与多发性硬化症患者的营养状况和临床状况相关的饮食总抗氧化能力
Fernanda Nunes Maia1, Bruna Yhang da Costa Silva2, Renan Souto Pereira1
1Postgraduate Program in Nutrition and Health, Ceará State University, Fortaleza, Brazil.
Nutritional neuroscience
|June 16, 2025
概括
患有MS (PwMS) 的人的饮食总抗氧化能力 (DTAC) 与营养状况有关. 较高的DTAC与脂肪增加相关,但可能会降低肌肉强度下降的可能性.
科学领域:
- 营养科学 营养科学
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 多发性硬化症 (MS) 是一种慢性神经系统疾病.
- 营养状况在疾病管理中起作用.
- 饮食中的抗氧化剂可能会影响MS的健康结果.
研究的目的:
- 为了确定MS (PwMS) 患者的饮食总抗氧化能力 (DTAC).
- 评估PwMS中DTAC,营养状况和疾病进展之间的关系.
主要方法:
- 这是一项涉及127名PwMS的横截面研究.
- 收集关于临床参数 (表型,EDSS,MRC尺度,MRI) 的数据.
- 评估营养状况 (BMI,BF%,WC) 和估计的DTAC从饮食摄入量.
主要成果:
- 较高的DTAC与腰围 (WC) 和身体脂肪百分比 (BF%) 的增加有关.
- 增加的DTAC也与更高的能量摄入量相关.
- 在DTAC和临床疾病参数 (EDSS,MRI病变) 之间没有发现关联.
- 较高的DTAC摄入量观察到下部肌肉力量的潜在减少.
结论:
- 鼓励健康的营养,特别是充足的饮食抗氧化剂摄入量,是建议PwMS.
- 需要进一步的研究才能充分理解DTAC在MS进展中的作用.
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