低纤维饮食与高风险的冠状动脉斑块特征有关
Ingrid Larsson1,2, Jiangming Sun3, Shafqat Ahmad4,5,6
1Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Cardiovascular research
|June 16, 2025
概括
低纤维和高红肉的饮食与高风险的冠状动脉斑块和动脉样硬化有关. 腰围,甘油三和高血压等代谢因素可能会调解这种关联,强调心脏保护性饮食.
科学领域:
- 心血管疾病的研究研究.
- 营养科学 营养科学
- 医学成像医学成像
背景情况:
- 饮食显著影响心血管疾病 (CVD),冠状动脉疾病是导致过早死亡的主要原因.
- 了解饮食对冠状动脉样硬化的影响,包括斑块特征,对于公共卫生至关重要.
研究的目的:
- 研究饮食模式与冠状动脉样硬化之间的关联,特别关注斑块特征.
- 为了确定饮食-动脉样硬化关系中的潜在调解者.
主要方法:
- 来自瑞典心肺生物图像研究 (SCAPIS) 的24,079名成年人 (50-64岁) 的横截面研究.
- 基于抗炎原则构建的饮食指数 (DI) (高植物性食品,低红色/加工肉和含糖饮料).
- 冠状动脉样硬化评估使用计算机断层扫描血管学,分析斑块类型和狭窄症的严重程度.
主要成果:
- 最低的DI三位数 (与最高相比) 与冠状动脉斑块 (44.3%与36.3%) 和狭窄 ≥50% (6.0%与3.7%) 的更高患病率有关.
- 低的DI与高风险的非化斑块与显著的狭窄 (1.5%与0.9%) 有关.
- 多变量分析表明,低DI与高风险斑块特征有关,腰围,甘油三和高血压是潜在的调解因素.
结论:
- 低纤维和高红肉的饮食与高风险的斑块特征,增加冠状动脉化和显著的狭窄有关.
- 代谢因素 (腰围,甘油三,高血压) 可能调解饮食和冠状动脉样硬化之间的联系.
- 这些发现强化了采用心脏保护性饮食建议的重要性.
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