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Updated: Sep 19, 2025

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
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一种piperidinyl indole衍生物,潜在的补充因子B抑制剂,在糖尿病病中起着保护作用

Zi-Han Li1,2,3,4,5,6, Zi-Jun Sun1,2,3,4,5,6,7, Dong-Yuan Chang1,2,3,4,5,6

  • 1Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China.

Diabetic medicine : a journal of the British Diabetic Association
|June 16, 2025
PubMed
概括

一种新型的piperidinyl indole衍生物通过向补充因子B (CFB) 来有效治疗小鼠的糖尿病病 (DN). 这种化合物减少损伤,炎症和纤维化,为DN提供了有前途的治疗策略.

关键词:
另一个替代路径路径.补充因子B抑制剂的抑制剂.糖尿病性脏病 糖尿病性脏病线粒体中的线粒体.这是一种piperidinyl indole衍生物.

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