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Updated: Sep 19, 2025

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
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与肥胖相关的血标志物对脂肪干细胞功能和表观遗传调节的影响

Andressa França Sousa Bispo1, Jussara de Jesus Simao1, Miguel Ambrizzi Moraes2

  • 1Postgraduate Program in Chemical Biology, Institute of Environmental Sciences, Chemical and Pharmaceutical, Federal University of São Paulo, Diadema, Brazil.

Obesity (Silver Spring, Md.)
|June 16, 2025
PubMed
概括

肥胖通过表观遗传变化破坏脂肪衍生的干细胞功能,特别是涉及勒丁信号传递,基因素修饰和炎症标志物. 这些变化损害了脂肪生成,并为代谢性疾病提供了潜在的治疗点.

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Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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