儿科肺移植期间的液体管理:单中心体验
Lifang Zhang1, Xinchen Tao1, Ge Luo1
1Department of Anesthesiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Translational pediatrics
|June 16, 2025
概括
在这项小型研究中,液体过载并没有显著影响小儿肺移植的结果. 需要更多的研究来确定儿科肺移植 (LTx) 的最佳流体管理策略.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 移植手术 移植手术 移植手术
- 流体管理流体管理
背景情况:
- 在儿科肺移植 (LTx) 中,手术内液体平衡至关重要.
- 流体过载 (FO) 对术后结果的影响尚不清楚.
- 本研究探讨了儿科LTx中的流体管理及其临床影响.
研究的目的:
- 调查手术内流体平衡对儿科肺移植术后结果的影响.
- 分析液体过载和诸如初级移植功能障碍 (PGD) 和急性损伤 (AKI) 等不良事件之间的关联.
主要方法:
- 20名儿科LTx患者的回顾性审查 (2019年7月-2023年8月).
- 患者分为流体过载 (FO) (≥10%的手术内流体平衡) 和非FO组.
- 术后结果的比较,包括PGD,AKI,机械通风持续时间和ICU停留时间.
主要成果:
- 在FO和非FO组之间,3级PGD,AKI,机械通风或ICU停留没有显著差异.
- 在PGD组中,血液产品和液体摄入量较高,但在统计学上并不显著.
- 该研究包括一个小样本大小 (n=20).
结论:
- 目前的证据不足以支持限制性流体策略,以减少儿科LTx.的不良结果.
- 需要进一步进行高质量的临床研究,以建立最佳的流体管理方案.
- 根据这项研究,无论是流体过载还是限制性方法,都没有最终提倡.
相关概念视频
Pneumonia V: Nursing management and Prevention
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
Acute Respiratory Failure-V
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Endoscopic Studies II: Thoracocentesis
Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant III: Nursing Management
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...


